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Species of Origin
Mouse
Expression system
CHO
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Affinity Tag
His Tag (C-term)
Buffer
Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
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Purity
>95% as determined by SDS-PAGE analysis.
Molecular weight
The protein has a calculated 44.4 MW of kDa.
The protein migrates as 45-60 kDa under reducing condition (SDS-PAGE analysis). -
Activity
Measured by its ability to bind human IgG in functional ELISA. Immobilized human IgG at 0.5 μg/mL (100μL/well) can bind Recombinant Mouse FcRn Protein.
Endotoxin level
<0.1 EU per 1 μg of the protein by the LAL method.
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Form
Lyophilized
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Specifications
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Background
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Background
Neonatal Fc receptor (FcRn) plays a role in regulating IgG homeostasis and transporting maternal antibodies to the fetus. It is being studied for its role in autoimmune diseases and therapeutic antibody delivery.
Synonyms
IgG receptor FcRn large subunit p51, FcRn, IgG Fc fragment receptor transporter alpha chain, Neonatal Fc receptor
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Uniprot ID
Q61559
P01887Sequence Note
Ser22-Ser297
Ile21-Met119
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Instruction
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Reconstitution
It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.
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Stability & Storage
This product is stable after storage at:
- -20°C for 12 months in lyophilized state from date of receipt.
- -20°C or -80°C for 1 month under sterile conditions after reconstitution.
Avoid repeated freeze/thaw cycles.
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Image
![SDS-PAGE analysis of recombinant Mouse FcRn.]()
SDS-PAGE analysis of recombinant Mouse FcRn.
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Publication
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Datasheet & Documents
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Disclaimer：For Research Use or Further Manufacturing Only.
