Leadgene Leadgene
Mouse DLL3, His Tag, CHO
Catalog Number

LDG120PMM

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  • Specifications
    • Species of Origin

      Mouse

      Expression system

      CHO

    • Affinity Tag

      His Tag (C-term)

      Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >90% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 49.64 kDa.
      The protein migrates as 35-50 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin level

      <0.1 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Background

      Delta-like 3 (DLL3) is a member of the Notch ligand family involved in embryonic development, particularly in somitogenesis. Unlike other Notch ligands, DLL3 acts as an inhibitor of Notch signaling. In mice, mutations in DLL3 result in skeletal defects, highlighting its role in vertebral segmentation. DLL3 has also been identified as a potential therapeutic target in certain cancers.

      Synonyms

      Delta-like protein 3, Drosophila Delta homolog 3, Delta3, M-Delta-3

    • Uniprot ID

      O88516

      Sequence Note

      His33-Leu490

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant mouse DLL3.

    SDS-PAGE analysis of recombinant mouse DLL3.

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  • Datasheet & Documents
    MSDS
    Manual
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