Leadgene Leadgene
Mouse CDH17, His Tag, CHO
Catalog Number

LDG105PMM

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  • Specifications
    • Species of Origin

      Mouse

      Expression system

      CHO

    • Affinity Tag

      His Tag (C-term)

      Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 85.13 kDa.
      The protein migrates as 100-130 kDa under reducing condition (SDS-PAGE analysis).

    • Activity

      Measured by its ability to bind mouse CDH17 Antibody in functional ELISA. Immobilized Recombinant mouse CDH17 Protein can bind mouse CDH17 Antibody.

      Endotoxin level

      <0.1 EU per 1 μg of the protein by the LAL method.

    • Form

      Lyophilized

  • Background
    • Background

      Cadherin-17 (CDH17), also known as liver-intestine cadherin, is a member of the cadherin superfamily. It is expressed in the gastrointestinal tract and plays a role in maintaining intestinal barrier function. CDH17 has been implicated in tumorigenesis, particularly in gastrointestinal cancers, by promoting cell proliferation and inhibiting apoptosis.

      Synonyms

      Cadherin-17, BILL-cadherin, Liver-intestine cadherin, LI-cadherin, P130

    • Uniprot ID

      Q9R100

      Sequence Note

      Phe26-Met786

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant mouse CDH17.

    SDS-PAGE analysis of recombinant mouse CDH17.

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  • Datasheet & Documents
    MSDS
    Manual
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