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Species of Origin
Mouse
Expression system
HEK293
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Affinity Tag
His Tag (C-term)
Buffer
Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
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Purity
>95% as determined by SDS-PAGE analysis.
Molecular weight
The protein has a calculated MW of 15.65 kDa.
The protein migrates as 23-35 kDa under reducing condition (SDS-PAGE analysis). -
Endotoxin level
<0.1 EU per 1 μg of the protein by the LAL method.
Form
Lyophilized
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Specifications
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Background
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Background
CD79B, also known as the Igβ chain, is a critical signaling component of the B-cell antigen receptor (BCR) complex. Together with CD79A (Igα), CD79B mediates antigen recognition and transduces activation signals required for B cell development, differentiation, and immune responses. Phosphorylation of CD79B initiates downstream signaling cascades, including SYK, BTK, and NF-κB pathways. Recombinant CD79B expressed in HEK293 cells is commonly used for antibody screening, BCR signaling studies, and immunological assay development.
Synonyms
Igβ, B29, MB-1 beta chain homolog, CD79 beta chain, CD79B antigen, Immunoglobulin-associated beta chain, B-cell receptor-associated protein β, Ig-beta protein, B-cell antigen receptor Igβ subunit, CD79B_MOUSE, BCR membrane signaling subunit, IgM receptor β chain, IgD receptor β chain, B lymphocyte antigen receptor beta chain, BCR complex component β, B-cell signaling adapter, β subunit of BCR complex, B-cell activation molecule, BCR scaffold protein, Immune receptor signal transduction protein, B-cell lineage surface protein, CD79b
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Uniprot ID
P15530
Sequence Note
Val26-Asp158
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Instruction
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Reconstitution
It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.
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Stability & Storage
This product is stable after storage at:
- -20°C for 12 months in lyophilized state from date of receipt.
- -20°C or -80°C for 1 month under sterile conditions after reconstitution.
Avoid repeated freeze/thaw cycles.
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Publication
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Datasheet & Documents
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Disclaimer:For Research Use or Further Manufacturing Only.