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Species of Origin
Mouse
Expression system
CHO
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Affinity Tag
His Tag (C-term)
Buffer
Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
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Purity
>95% as determined by SDS-PAGE analysis.
Molecular weight
The protein has a calculated MW of 18.96 kDa.
The protein migrates as 12-27 kDa under reducing condition (SDS-PAGE analysis). -
Endotoxin level
<0.1 EU per 1 μg of the protein by the LAL method.
Form
Lyophilized
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Specifications
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Background
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Background
CD40 is a cell surface receptor belonging to the tumor necrosis factor (TNF) receptor superfamily, expressed primarily on antigen-presenting cells such as B cells, dendritic cells, and macrophages. It plays a pivotal role in immune responses by mediating interactions between these cells and T cells, crucial for antibody production, inflammation, and immune regulation. Our product targets CD40 to modulate these signaling pathways, potentially influencing immune activation and response. Through extensive research, we have developed a solution designed to interact selectively with CD40, offering a specialized approach for therapeutic interventions in conditions where immune dysregulation is a concern.
Synonyms
Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor
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Uniprot ID
P27512
Sequence Note
Met1-Arg193
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Instruction
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Reconstitution
It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.
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Stability & Storage
This product is stable after storage at:
- -20°C for 12 months in lyophilized state from date of receipt.
- -20°C or -80°C for 1 month under sterile conditions after reconstitution.
Avoid repeated freeze/thaw cycles.
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Review
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Publication
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Datasheet & Documents
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Disclaimer:For Research Use or Further Manufacturing Only.