Leadgene Leadgene
Mouse CD147, His Tag, CHO
Catalog Number

LDG091PMM

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  • Specifications
    • Species of Origin

      Mouse

      Expression system

      CHO

    • Affinity Tag

      His Tag (C-term)

      Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 24.84 kDa.
      The protein migrates as 20-40 kDa under reducing condition (SDS-PAGE analysis).

    • Activity

      Measured by its ability to bind SARS-CoV2 spike protein(RBD) in functional ELISA. Immobilized Recombinant SARS-CoV2 spike protein(RBD) at 5 μg/mL (100 μL/well) can bind Recombinant Mouse CD147 Protein.

      Endotoxin level

      <0.1 EU per 1 μg of the protein by the LAL method.

    • Form

      Lyophilized

  • Background
    • Background

      CD147 (Basigin), also known as EMMPRIN, is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. It functions as an extracellular matrix metalloproteinase inducer, regulating cell adhesion, migration, and invasion. CD147 plays critical roles in immune regulation, inflammation, and tumor progression. It is widely studied as a biomarker and therapeutic target in cancer, cardiovascular disease, and infectious pathologies.

      Synonyms

      Basigin, Basic immunoglobulin superfamily, HT7 antigen, Membrane glycoprotein gp42, CD147, BSG, Basigin (Ok Blood Group), EMMPRIN

    • Uniprot ID

      NP_001070652.1

      Sequence Note

      Ala22-Ala211

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant mouse CD147.

    SDS-PAGE analysis of recombinant mouse CD147.

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  • Datasheet & Documents
    MSDS
    Manual
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Disclaimer:For Research Use or Further Manufacturing Only.

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