Human TIGIT, His Tag, CHO

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Catalog Number

LDG050PHM

Datasheet

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• Specifications

  • Species of Origin

    Human

    Expression system

    CHO

  • Affinity Tag

    His Tag (C-term)

    Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

  • Purity

    >95% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated MW of 13.89 kDa.
    The protein migrates as 13-20 kDa under reducing condition (SDS-PAGE analysis).

  • Activity

    Measured by flow cytometry for its ability to bind a ligand expressed in A549 human lung carcinoma epithelial cell.

    Endotoxin level

    <0.1 EU per 1 μg of the protein by the LAL method.

  • Form

    Lyophilized

• Background

  • Background

    TIGIT (T cell immunoreceptor with Ig and ITIM domains) is a crucial immune checkpoint protein involved in regulating immune responses. It interacts with ligands such as CD155 to inhibit T cell and NK cell functions, influencing immune tolerance and responses in diseases like cancer and autoimmunity. This protein is essential for studying immune modulation and developing targeted therapies. Explore its potential applications in immunotherapy and immunology research to advance understanding and treatment strategies for immune-related disorders.

    Synonyms

    T-cell immunoreceptor with Ig and ITIM domains, VSIG9, VSTM3

  • Uniprot ID

    Q495A1

    Sequence Note

    Met1- Pro141

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  HPLC analysis of recombinant Human TIGIT, His Tag, CHO.
  The purity of Human TIGIT Protein is greater than 95% as determined by RP-HPLC.

  SDS-PAGE analysis of recombinant human TIGIT.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.