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Leadgene Leadgene
Human PROS1, His-SUMO Tag, E. coli
Catalog Number

LDG182PHE

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  • Specifications
    • Species of Origin

      Human

      Expression system

      Escherichia coli

    • Affinity Tag

      His-SUMO Tag (N-term)

      Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 82.89 kDa.
      The protein migrates as 75 kDa uder reducing condition (SDS-PAGE analysis).

    • Endotoxin level

      <1.0 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Background

      PROS1, also known as protein S, is a vitamin K-dependent protein that plays a crucial role in the regulation of blood coagulation. It functions as a cofactor for protein C, another key player in the coagulation cascade.

      PROS1 acts as an anticoagulant by inhibiting the activity of certain clotting factors and promoting the breakdown of blood clots. It helps maintain the balance between clotting and anticoagulation, preventing the formation of excessive blood clots that can lead to thrombosis.

      Synonyms

      PROS, Vitamin K-dependent protein S

    • Uniprot ID

      # P07225

      Sequence Note

      Ala42-Ser676

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant human PROS1.

    SDS-PAGE analysis of recombinant human PROS1.

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  • Datasheet & Documents
    MSDS
    Manual
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