Leadgene Leadgene
Human NKp30, His Tag, CHO
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Catalog Number

LDG139PHM

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  • Specifications
    • Species of Origin

      Human

      Expression system

      CHO

    • Affinity Tag

      His Tag (C-term)

      Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 13.65 kDa.
      The protein migrates as 20-25 kDa under reducing condition (SDS-PAGE analysis).

    • Activity

      Measured by flow cytometry for its ability to bind a ligand expressed in K562 human chronic myelogenous leukemia cells.

      Endotoxin level

      <0.1 EU per 1 μg of the protein by the LAL method.

    • Form

      Lyophilized

  • Background
    • Background

      Natural cytotoxicity triggering receptor 3 (NKp30), also known as CD337, is an activating receptor expressed on natural killer (NK) cells. It plays a crucial role in NK cell-mediated cytotoxicity against tumor and virus-infected cells by recognizing ligands such as B7-H6 and heparan sulfate glycosaminoglycans. NKp30 is also involved in the cross-talk between NK cells and dendritic cells, influencing immune responses.

      Synonyms

      Natural cytotoxicity triggering receptor 3, Activating natural killer receptor p30, Natural killer cell p30-related protein, NK-p30, NKp30, CD337

    • Uniprot ID

      O14931

      Sequence Note

      Leu19-Gly135

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    HPLC analysis of recombinant Human NKp30, His Tag, CHO. The purity of Human NKp30 Protein is greater than 95% as determined by RP-HPLC.

    HPLC analysis of recombinant Human NKp30, His Tag, CHO.
    The purity of Human NKp30 Protein is greater than 95% as determined by RP-HPLC.

    SDS-PAGE analysis of recombinant Human NKp30.

    SDS-PAGE analysis of recombinant Human NKp30.

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  • Datasheet & Documents
    MSDS
    Manual
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Disclaimer:For Research Use or Further Manufacturing Only.

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