Leadgene Leadgene
Human NGFR, His Tag, HEK293
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Catalog Number

LDG061PHM

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  • Specifications
    • Species of Origin

      Human

      Expression system

      HEK293

    • Affinity Tag

      His Tag (C-term)

      Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 24.38 kDa.
      The protein migrates as 35-50 kDa under reducing condition (SDS-PAGE analysis).

    • Activity

      Measured by its ability to bind human beta-NGF in functional ELISA. Immobilized Recombinant human beta-NGF at 5 μg/mL (100 μL/well) can bind Recombinant Human NGFR Protein.

      Endotoxin level

      <0.1 EU per 1 μg of the protein by the LAL method.

    • Form

      Lyophilized

  • Background
    • Background

      Human nerve Growth Factor Receptor (NGFR), also known as p75NTR, is a receptor for neurotrophins, including nerve growth factor. It is involved in the regulation of neuronal survival, growth, and apoptosis, playing a key role in the nervous system development and injury response.

      Synonyms

      Tumor necrosis factor receptor superfamily member 16, Gp80-LNGFR, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, NGF receptor, Low-affinity nerve growth factor receptor p75NGFR, Low-affinity nerve growth factor receptor p75NGR, p75 ICD, CD271

    • Uniprot ID

      P08138

      Sequence Note

      Lys29-Asn 250

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    Activity analysis of recombinant Human NGFR, His Tag, HEK293. Measured by its ability to bind human beta-NGF in functional ELISA. Immobilized Recombinant human beta-NGF at 5 μg/mL (100 μL/well) can bind Recombinant Human NGFR Protein.

    Activity analysis of recombinant Human NGFR, His Tag, HEK293.
    Measured by its ability to bind human beta-NGF in functional ELISA. Immobilized Recombinant human beta-NGF at 5 μg/mL (100 μL/well) can bind Recombinant Human NGFR Protein.

    HPLC analysis of recombinant Human NGFR, His Tag, HEK293. The purity of Human NGFR Protein is greater than 95% as determined by RP-HPLC.

    HPLC analysis of recombinant Human NGFR, His Tag, HEK293.
    The purity of Human NGFR Protein is greater than 95% as determined by RP-HPLC.

    SDS-PAGE analysis of recombinant Human NGFR.

    SDS-PAGE analysis of recombinant Human NGFR.

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  • Datasheet & Documents
    MSDS
    Manual
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Disclaimer:For Research Use or Further Manufacturing Only.

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