Leadgene Leadgene
Human MUC1, His Tag, CHO
Catalog Number

LDG135PHM

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  • Specifications
    • Species of Origin

      Human

      Expression system

      CHO

    • Affinity Tag

      His Tag (C-term)

      Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 34.56 kDa.
      The protein migrates as 45-60 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin level

      <0.1 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Background

      MUC1 (Mucin-1, also known as CD227) is a membrane-bound glycoprotein expressed on the surface of epithelial cells. It is overexpressed and aberrantly glycosylated in many adenocarcinomas, making it a key tumor-associated antigen and biomarker in cancer diagnostics and immunotherapy research.

      Synonyms

      MUC1, Mucin-1, CD227, PEM, episialin, EMA, CA15-3 antigen, H23AG, KL-6, MAM6, MUC-1, SEC, PEMT, PUM

    • Uniprot ID

      P15941

      Sequence Note

      Ser 24-Ser 380

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant Human MUC1.

    SDS-PAGE analysis of recombinant Human MUC1.

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Disclaimer:For Research Use or Further Manufacturing Only.

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