Human Lipoprotein(a) (KIV5-6), His Tag, E. coli

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Catalog Number

LDG195PHE

Datasheet

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• Specifications

  • Species of Origin

    Human

    Expression system

    Escherichia coli

  • Affinity Tag

    His Tag (C-term)

    Buffer

    Lyophilized from a 0.2 µm filtered solution of 10 mM Sodium phosphate, 0.75 mM SDS, pH 7.0.

  • Purity

    >95% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated MW of 18.95 kDa.
    The protein migrates as 16-20 kDa under reducing condition (SDS-PAGE analysis).

  • Endotoxin level

    <0.1 EU per 1 μg of the protein by the LAL method.

    Form

    Lyophilized

• Background

  • Background

    Human Lipoprotein(a) [Lp(a)] is a low-density lipoprotein–like particle in which apolipoprotein(a) [Apo(a)] is covalently linked to apolipoprotein B-100. Variants containing specific kringle IV (KIV) domains, such as KIV5-6, are useful for investigating structure–function relationships and the genetic risk of atherosclerosis, coronary artery disease, and thrombosis. Recombinant Lp(a) fragments provide valuable tools for cardiovascular research and in vitro diagnostic development.

    Synonyms

    Lp(a), Apolipoprotein(a), Apo(a), Lipoprotein little a, Kringle IV-5/6 fragment, Kringle domain protein, Cardiovascular risk factor Lp(a), Apo(a) KIV variant, Lipoprotein(a) isoform, KIV5-6, LPA

  • Uniprot ID

    P08519

    Sequence Note

    Glu483-Cys561 & Glu597-Cys675

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  HPLC analysis of recombinant Human Lipoprotein(a) (KIV5-6), His Tag, E. coli.
  The purity of Human Lipoprotein(a) (KIV5-6) is greater than 95% as determined by SEC-HPLC.

  SDS-PAGE analysis of recombinant human lipoprotein(a) (KIV5-6) protein.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.