Leadgene Leadgene
Human IL-15, Fc Tag, CHO
Catalog Number

LDG175PHM

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  • Specifications
    • Species of Origin

      Human

      Expression system

      CHO

    • Affinity Tag

      Human IgG1 Fc Tag (N-term)
      His-Avi Tag (C-term)

      Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 42.36 kDa.
      The protein migrates as 42-58 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin level

      <0.1 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Background

      Interleukin-15 (IL-15) is a crucial cytokine that promotes the development, proliferation, and survival of NK cells and CD8+ T cells. Unlike IL-2, it's often presented in trans via a cell-associated receptor, boosting both innate and adaptive immunity. This makes IL-15 vital for anti-tumor immunity and fighting viral infections, positioning it as a key focus in immunotherapy research.

      Synonyms

      IL-15, MGC9721, TNFSF14A, AG-IL-15-1, Interleukin 15, IL15, UNQ307/PRO353, T-cell activation cytokine, Natural killer cell stimulating factor

    • Uniprot ID

      P40933

      Sequence Note

      Asn49-Ser162

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant Human IL-15.

    SDS-PAGE analysis of recombinant Human IL-15.

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  • Datasheet & Documents
    MSDS
    Manual
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