Leadgene Leadgene
Human IGF-1R, His Tag, CHO
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Catalog Number

LDG155PHM

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  • Specifications
    • Species of Origin

      Human

      Expression system

      CHO

    • Affinity Tag

      His Tag (C-term)

      Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >90% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 106.64 kDa.
      The protein migrates as 120-200 kDa under reducing condition (SDS-PAGE analysis).

    • Activity

      Measured by its ability to bind human IGF-I in functional ELISA. Immobilized Recombinant human IGF-I Protein at 2 μg/mL (100 μL/well) can bind Recombinant Human IGF-1R Protein.

      Endotoxin level

      <0.1 EU per 1 μg of the protein by the LAL method.

    • Form

      Lyophilized

  • Background
    • Background

      Insulin-like growth factor 1 receptor (IGF-1R) is a transmembrane receptor tyrosine kinase that mediates the effects of IGF-1. It plays a critical role in growth and development and is involved in various cellular processes, including proliferation, differentiation, and apoptosis.

      Synonyms

      Insulin-like growth factor 1 receptor, EC:2.7.10.1, Insulin-like growth factor I receptor, IGF-I receptor, CD221, Cleaved into: Insulin-like growth factor 1 receptor alpha chain, Insulin-like growth factor 1 receptor beta chain

    • Uniprot ID

      P08069

      Sequence Note

      Glu31-Asn932

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    HPLC analysis of recombinant Human IGF-1R, His Tag, CHO. The purity of Human IGF-1R Protein is greater than 95% as determined by RP-HPLC.

    HPLC analysis of recombinant Human IGF-1R, His Tag, CHO.
    The purity of Human IGF-1R Protein is greater than 95% as determined by RP-HPLC.

    SDS-PAGE analysis of recombinant human IGF-1R.

    SDS-PAGE analysis of recombinant human IGF-1R.

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  • Datasheet & Documents
    MSDS
    Manual
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Disclaimer:For Research Use or Further Manufacturing Only.

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