Human IGF-1R, His Tag, CHO

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Catalog Number

LDG155PHM

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• Specifications

  • Species of Origin

    Human

    Expression system

    CHO

  • Affinity Tag

    His Tag (C-term)

    Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

  • Purity

    >90% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated MW of 106.64 kDa.
    The protein migrates as 120-200 kDa under reducing condition (SDS-PAGE analysis).

  • Activity

    Measured by its ability to bind human IGF-I in functional ELISA. Immobilized Recombinant human IGF-I Protein at 2 μg/mL (100 μL/well) can bind Recombinant Human IGF-1R Protein.

    Endotoxin level

    <0.1 EU per 1 μg of the protein by the LAL method.

  • Form

    Lyophilized

• Background

  • Background

    Insulin-like growth factor 1 receptor (IGF-1R) is a transmembrane receptor tyrosine kinase that mediates the effects of IGF-1. It plays a critical role in growth and development and is involved in various cellular processes, including proliferation, differentiation, and apoptosis.

    Synonyms

    Insulin-like growth factor 1 receptor, EC:2.7.10.1, Insulin-like growth factor I receptor, IGF-I receptor, CD221, Cleaved into: Insulin-like growth factor 1 receptor alpha chain, Insulin-like growth factor 1 receptor beta chain

  • Uniprot ID

    P08069

    Sequence Note

    Glu31-Asn932

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  HPLC analysis of recombinant Human IGF-1R, His Tag, CHO.
  The purity of Human IGF-1R Protein is greater than 95% as determined by RP-HPLC.

  SDS-PAGE analysis of recombinant human IGF-1R.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.