Leadgene Leadgene
Human Galectin-10, His Tag, E. coli
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  • Specifications
    • Species of Origin


      Expression system

      Escherichia coli

    • Affinity Tag

      His Tag (N-term)


      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >98% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 16.31 kDa.
      The protein migrates as 16-19 kDa under reducing condition (SDS-PAGE analysis).

    • Activity

      Measure by its ability to chemoattract human THP1 cells using a concentration range of 0.2-25 µg/mL.

      Endotoxin level

      <0.1 EU per 1 μg of the protein by the LAL method.

    • Form


  • Background
    • Background

      Galectin-10 (Gal-10) is a lectin family member and is one of the prototype galectins. It contains one carbohydrate recognition domain (CRD), responsible for β-galactoside binding, and is biologically active as homodimers. It has been reported that galectin-10 is presented in eosinophils but also detected in basophils and macrophages. Accumulated evidence indicates that galectin-10 spontaneously forms Charcot-Leyden crystals (CLCs), participating in allergic responses and related inflammatory reactions. Several binding partners for galectin-10 have been identified, including eosinophil granule cationic ribonucleases, eosinophil-derived neurotoxin (EDN, RNS2), and eosinophil cationic protein (ECP, RNS3), demonstrating the interaction is essential for eosinophil differentiation and granulogenesis.


      Gal-10, Charcot-Leyden crystal protein, CLC, Eosinophil lysophospholipase, Lysolecithin acylhydrolase

    • Uniprot ID


      Sequence Note


  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.


      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant human Galectin-10.

    SDS-PAGE analysis of recombinant human Galectin-10.

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  • Datasheet & Documents

Disclaimer:For Research Use or Further Manufacturing Only.

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