Leadgene Leadgene
Human FLT-3, His Tag, CHO
Catalog Number

LDG167PHM

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  • Specifications
    • Species of Origin

      Human

      Expression system

      CHO

    • Affinity Tag

      His-Avi (C-term)

      Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 59.03 kDa.
      The protein migrates as 75-135 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin level

      <0.1 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Background

      Human FLT-3 (Fms-like tyrosine kinase 3, also known as CD135) is a class III receptor tyrosine kinase expressed on hematopoietic progenitor cells. It plays a critical role in regulating cell proliferation and differentiation, especially in dendritic cells and B cell progenitors. FLT-3 mutations are commonly associated with acute myeloid leukemia (AML).

      Synonyms

      CD135, FLK2, STK-1, FLT3 receptor, Fms-related tyrosine kinase 3, Flt3, Flt-3

    • Uniprot ID

      P49771

      Sequence Note

      Thr27-Pro185

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant Human FLT-3.

    SDS-PAGE analysis of recombinant Human FLT-3.

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  • Datasheet & Documents
    MSDS
    Manual
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Disclaimer:For Research Use or Further Manufacturing Only.

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