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Species of Origin
Human
Expression system
CHO
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Affinity Tag
His-Avi (C-term)
Buffer
Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
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Purity
>95% as determined by SDS-PAGE analysis.
Molecular weight
The protein has a calculated MW of 59.03 kDa.
The protein migrates as 75-135 kDa under reducing condition (SDS-PAGE analysis). -
Endotoxin level
<0.1 EU per 1 μg of the protein by the LAL method.
Form
Lyophilized
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Specifications
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Background
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Background
Human FLT-3 (Fms-like tyrosine kinase 3, also known as CD135) is a class III receptor tyrosine kinase expressed on hematopoietic progenitor cells. It plays a critical role in regulating cell proliferation and differentiation, especially in dendritic cells and B cell progenitors. FLT-3 mutations are commonly associated with acute myeloid leukemia (AML).
Synonyms
CD135, FLK2, STK-1, FLT3 receptor, Fms-related tyrosine kinase 3, Flt3, Flt-3
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Uniprot ID
P49771
Sequence Note
Thr27-Pro185
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Instruction
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Reconstitution
It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.
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Stability & Storage
This product is stable after storage at:
- -20°C for 12 months in lyophilized state from date of receipt.
- -20°C or -80°C for 1 month under sterile conditions after reconstitution.
Avoid repeated freeze/thaw cycles.
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Publication
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Datasheet & Documents
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Disclaimer:For Research Use or Further Manufacturing Only.