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Species of Origin
Human
Expression system
CHO
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Affinity Tag
His-Avi (C-term)
Buffer
Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
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Purity
>90% as determined by SDS-PAGE analysis.
Molecular weight
The protein has a calculated MW of 65.5kDa.
The protein migrates as 40-60 kDa under reducing condition (SDS-PAGE analysis). -
Endotoxin level
<0.1 EU per 1 μg of the protein by the LAL method.
Form
Lyophilized
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Specifications
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Background
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Background
Complement C3b is a central protein fragment generated from the cleavage of complement component C3, playing a crucial role in the activation of the complement system. C3b functions as an opsonin, tagging pathogens for phagocytosis, and participates in the formation of C5 convertase. It is essential in innate immunity, pathogen clearance, and modulation of adaptive immune responses, making it a valuable tool in immunology and infectious disease research.
Synonyms
C3b fragment, Complement component 3b, Opsonic fragment, C3 beta chain, Beta chain of complement C3
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Uniprot ID
P05156
Sequence Note
Lys19-Val583
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Instruction
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Reconstitution
It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.
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Stability & Storage
This product is stable after storage at:
- -20°C for 12 months in lyophilized state from date of receipt.
- -20°C or -80°C for 1 month under sterile conditions after reconstitution.
Avoid repeated freeze/thaw cycles.
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Review
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Publication
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Datasheet & Documents
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Disclaimer:For Research Use or Further Manufacturing Only.