Leadgene Leadgene
Human CD70, His Tag, CHO
Catalog Number

LDG088PHM

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  • Specifications
    • Species of Origin

      Human

      Expression system

      CHO

    • Affinity Tag

      His Tag (N-term)

      Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >85% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 17.95 kDa.
      The protein migrates as kDa under reducing condition (SDS-PAGE analysis).

    • Activity

      Measured by its ability to bind human CD27 in functional ELISA. Immobilized Recombinant human CD27 Protein at 2 μg/mL (100 μL/well) can bind Recombinant Human CD70 Protein.

      Endotoxin level

      <0.1 EU per 1 μg of the protein by the LAL method.

    • Form

      Lyophilized

  • Background
    • Background

      CD70 is a ligand for the CD27 receptor and is involved in T-cell activation and immune regulation. It is also implicated in various cancers.

      Synonyms

      CD70 antigen, CD27 ligand, CD27-L, Tumor necrosis factor ligand superfamily member 7, CD70, CD27LG, TNFSF7, TNFSF7G, CD27L

    • Uniprot ID

      P32970

      Sequence Note

      Gln39-Pro193

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant human CD70.

    SDS-PAGE analysis of recombinant human CD70.

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  • Datasheet & Documents
    MSDS
    Manual
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