Leadgene Leadgene
Human CD63, His Tag, CHO
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Catalog Number

LDG043PHM

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  • Specifications
    • Species of Origin

      Human

      Expression system

      CHO

    • Affinity Tag

      His Tag (C-term)

      Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 12.35 kDa.
      The protein migrates as 12-35 kDa under reducing condition (SDS-PAGE analysis).

    • Activity

      Measured by flow cytometry for its ability to bind a ligand expressed in U-937 human histiocytic lymphoma cells.

      Endotoxin level

      <0.1 EU per 1 μg of the protein by the LAL method.

    • Form

      Lyophilized

  • Background
    • Background

      CD63 is a transmembrane protein belonging to the tetraspanin family, crucial for intracellular trafficking and exosome biogenesis. It is widely expressed on various cell types, including immune cells and platelets, playing roles in cell adhesion, activation, and antigen presentation. Our product targets CD63 to potentially modulate these cellular processes, influencing immune responses and cellular communication. Through meticulous research, we have developed a solution designed to interact selectively with CD63, offering a promising approach for therapeutic interventions in immune-related disorders and exosome-mediated communications.

      Synonyms

      Granulophysin, Lysosomal-associated membrane protein 3, Lysosome integral membrane protein 1, Melanoma-associated antigen ME491, OMA81H, Ocular melanoma-associated antigen, Tetraspanin-30, (Tspan-30)

    • Uniprot ID

      P08962 

      Sequence Note

      Ala 103-Val 203

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    HPLC analysis of recombinant Human CD63, His Tag, CHO. The purity of Human CD63 Protein is greater than 90% as determined by RP-HPLC.

    HPLC analysis of recombinant Human CD63, His Tag, CHO.
    The purity of Human CD63 Protein is greater than 90% as determined by RP-HPLC.

    SDS-PAGE analysis of recombinant Human CD63.

    SDS-PAGE analysis of recombinant Human CD63.

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  • Datasheet & Documents
    MSDS
    Manual
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