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Catalog Number

LDG047PHM

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Specifications
- Species of Origin
  
  Human
  
  Expression system
  
  CHO
- Affinity Tag
  
  His Tag (C-term)
  
  Buffer
  
  Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
- Purity
  
  >95% as determined by SDS-PAGE analysis.
  
  Molecular weight
  
  The protein has a calculated MW of 41.52 kDa.
  The protein migrates as 45-47 kDa under reducing condition (SDS-PAGE analysis).
- Activity
  
  Measured by its ability to support the adhesion of NIH-3T3 mouse embryonic fibroblast cells, with the ED50 ranging from 1 to 5 μg/mL.
  
  Endotoxin level
  
  <0.1 EU per 1 μg of the protein by the LAL method.
- Form
  
  Lyophilized
Background
- Background
  
  CD4 is a glycoprotein expressed on the surface of T helper cells, crucial for immune system regulation. It facilitates interactions between T cells and antigen-presenting cells, pivotal in initiating and coordinating immune responses. Our product targets CD4 to modulate these interactions, potentially influencing immune function. Through extensive research, we have developed a solution designed to interact selectively with CD4, aiming to optimize immune response modulation for therapeutic benefits.
  
  Synonyms
  
  T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4, CD4 antigen, T-helper antigen, L3T4, T4 antigen, HIV receptor
- Uniprot ID
  
  P01730
  
  Sequence Note
  
  Met1-Trp390
Instruction
- Reconstitution
  
  It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
  
  Shipping
  
  The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.
- Stability & Storage
  
  This product is stable after storage at:
  - -20°C for 12 months in lyophilized state from date of receipt.
  - -20°C or -80°C for 1 month under sterile conditions after reconstitution.
  Avoid repeated freeze/thaw cycles.
Image

HPLC analysis of recombinant Human CD4, His Tag, CHO.
The purity of Human CD4 Protein is greater than 90% as determined by SEC-HPLC.

SDS-PAGE analysis of recombinant human CD4 protein.

Human CD4, His Tag, CHO supports the adhesion of NIH-3T3 mouse embryonic fibroblast cells, with the ED50 ranging from 1 to 5 μg/mL.

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Datasheet & Documents

Datasheet

MSDS

Manual

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