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Leadgene Leadgene
Human CAM6, His Tag, CHO
Catalog Number

LDG032PHM

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  • Specifications
    • Species of Origin

      Human

      Expression system

      CHO

    • Affinity Tag

      His Tag (C-term)

      Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 32.06 kDa.
      The protein migrates as 40-55 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin level

      <0.1 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Background

      CAM6 (Cell Adhesion Molecule 6) protein, also known as Carcinoembryonic Antigen-related Cell Adhesion Molecule 6 (CEACAM6), is a transmembrane glycoprotein involved in cell-cell adhesion and signaling. It is expressed in various epithelial tissues and is overexpressed in certain cancers, including colorectal, pancreatic, and lung cancer. CAM6 promotes cancer cell proliferation, migration, and invasion, contributing to tumor progression and metastasis. Additionally, CAM6 can serve as a biomarker for cancer diagnosis and prognosis. Understanding CAM6's roles in cancer biology is crucial for developing targeted therapies and diagnostic tools for cancer detection and treatment.

      Synonyms

      Carcinoembryonic antigen-related cell adhesion molecule 6, Non-specific crossreacting antigen, Normal cross-reacting antigen, CD66c

    • Uniprot ID

      P40199

      Sequence Note

      Met1-Gly320

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in 4 mM HCl to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant human CAM6.

    SDS-PAGE analysis of recombinant human CAM6.

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  • Datasheet & Documents
    MSDS
    Manual
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