Leadgene Leadgene
Human BLyS, His Tag, CHO
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Catalog Number

LDG046PHM

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  • Specifications
    • Species of Origin

      Human

      Expression system

      CHO

    • Affinity Tag

      His Tag (C-term)

      Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 17.87 kDa.
      The protein migrates as 16-18 kDa under reducing condition (SDS-PAGE analysis).

    • Activity

      Measured by its ability to bind human BAFF in functional ELISA. Immobilized Recombinant human BAFF Protein at 1 μg/mL (100 μL/well) can bind Recombinant Human BLyS Protein.

      Endotoxin level

      <0.1 EU per 1 μg of the protein by the LAL method.

    • Form

      Lyophilized

  • Background
    • Background

      BLyS (B Lymphocyte Stimulator), also known as BAFF (B-cell Activating Factor), is a cytokine crucial for B-cell survival and maturation. It plays a key role in regulating B-cell homeostasis and antibody production. Our product targets BLyS to modulate B-cell activity, potentially influencing immune responses in conditions like autoimmune diseases and B-cell malignancies. Through advanced scientific research, we have developed a solution aimed at selectively interacting with BLyS, offering a promising approach to therapeutic intervention in disorders where B-cell dysregulation is a concern.

      Synonyms

      Tumor necrosis factor ligand superfamily member 13B, B lymphocyte stimulator (BLyS), B-cell-activating factor, BAFF, Dendritic cell-derived TNF-like molecule, TNF- and APOL-related leukocyte expressed ligand 1 (TALL-1), CD257

    • Uniprot ID

      GenBank: AAH20674.1

      Sequence Note

      Ala134-Leu285

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    HPLC analysis of recombinant Human BLyS, His Tag, CHO. The purity of Human BLyS Protein is greater than 95% as determined by RP-HPLC.

    HPLC analysis of recombinant Human BLyS, His Tag, CHO.
    The purity of Human BLyS Protein is greater than 95% as determined by RP-HPLC.

    SDS-PAGE analysis of recombinant Human BLyS.

    SDS-PAGE analysis of recombinant Human BLyS.

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  • Datasheet & Documents
    MSDS
    Manual
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Disclaimer:For Research Use or Further Manufacturing Only.

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