Human ApoJ, His Tag, HEK293

Catalog Number

LDG077PHM

Datasheet

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• Specifications

  • Species of Origin

    Human

    Expression system

    HEK293

  • Affinity Tag

    His Tag (C-term)

    Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4

  • Purity

    >95% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated MW of 47.79 kDa.
    The protein migrates as 50-70 kDa under reducing condition (SDS-PAGE analysis).

  • Endotoxin level

    <1 EU per 1 μg of the protein by the LAL method.

    Form

    Lyophilized

• Background

  • Background

    Apolipoprotein J, also known as clusterin, is a multifunctional protein involved in lipid transport, immune response, and cellular processes. It plays a crucial role in the metabolism of lipoproteins and is found in various tissues, including the brain and liver. Apolipoprotein J is known for its involvement in neurodegenerative diseases, such as Alzheimer's, where it may contribute to the clearance of amyloid-beta plaques. Additionally, it acts as a chaperone, protecting cells from stress and promoting tissue repair. Its diverse functions make it a significant biomarker for various diseases and a potential target for therapeutic interventions.

    Synonyms

    Clusterin, CLU, Aging-associated gene 4 protein, Apolipoprotein J, Complement cytolysis inhibitor, Complement-associated protein SP-40,40, Ku70-binding protein 1, NA1/NA2, Sulfated glycoprotein 2, Testosterone-repressed prostate message 2

  • Uniprot ID

    P10909

    Sequence Note

    Asp23-Glu449, with a deletion of Arg214-Leu238.

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  SDS-PAGE analysis of recombinant Human ApoJ.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.