Leadgene Leadgene
Human Amyloid Beta, His Tag, CHO
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Catalog Number

LDG119PHM

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  • Specifications
    • Species of Origin

      Human

      Expression system

      CHO

    • Affinity Tag

      His Tag (C-term)

      Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 72.74 kDa.
      The protein migrates as 90-120 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin level

      <0.1 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Background

      Amyloid beta (Aβ) peptides are key components of amyloid plaques in Alzheimer’s disease, contributing to neurotoxicity, synaptic dysfunction, and neurodegeneration.

      Synonyms

      Amyloid-beta precursor protein, APP, ABPP, APPI, Alzheimer disease amyloid A4 protein homolog, Alzheimer disease amyloid protein, Amyloid precursor protein, Amyloid-beta (A4) precursor protein, Amyloid-beta A4 protein, Cerebral vascular amyloid peptide, CVAP, PreA4, Protease nexin-II, PN-II, Cleaved into: N-APP, Soluble APP-alpha, S-APP-alpha, Soluble APP-beta, S-APP-beta, C99, Beta-secretase C-terminal fragment, Beta-CTF, Amyloid-beta protein 42, Abeta42, Beta-APP42, Amyloid-beta protein 40, Abeta40, Beta-APP40, C83, Alpha-secretase C-terminal fragment, Alpha-CTF, P3(42), P3(40), C80, Gamma-secretase C-terminal fragment 59, Amyloid intracellular domain 59, AICD-59, AID(59), Gamma-CTF(59), Gamma-secretase C-terminal fragment 57, Amyloid intracellular domain 57, AICD-57, AID(57), Gamma-CTF(57), Gamma-secretase C-terminal fragment 50, Amyloid intracellular domain 50, AICD-50, AID(50), Gamma-CTF(50), C31

    • Uniprot ID

      P05067-8

      Sequence Note

      Leu18-Met652

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    HPLC analysis of recombinant Human Amyloid Beta, His Tag, CHO. The purity of Human Amyloid Beta Protein is greater than 95% as determined by RP-HPLC.

    HPLC analysis of recombinant Human Amyloid Beta, His Tag, CHO.
    The purity of Human Amyloid Beta Protein is greater than 95% as determined by RP-HPLC.

    SDS-PAGE analysis of recombinant Human Amyloid beta.

    SDS-PAGE analysis of recombinant Human Amyloid beta.

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  • Datasheet & Documents
    MSDS
    Manual
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