Enterovirus A71 (EV-A71) VP1 Protein, His Tag, E. coli

Catalog Number

LDG029PVE

Datasheet

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• Specifications

  • Species of Origin

    Enterovirus A71

    Expression system

    Escherichia coli

  • Affinity Tag

    His Tag (C-term)

    Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

  • Purity

    >95% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated MW of 33.76 kDa.
    The protein migrates as 35 kDa under reducing condition (SDS-PAGE analysis).

  • Form

    Lyophilized

• Background

  • Background

    Enterovirus A71 (EV-A71), a positive-strand RNA virus of the Picornaviridae family, is a persisting global concern. EV-A71 is primarily transmitted through the fecal-oral route, causing hand, foot, and mouth disease (HFMD), severe central nervous system complications, neural damage, and even life-threatening. VP1 is a structural capsid protein consisting of 297 amino acids, promoting infection by binding to specific receptors on the surface of host cells, including P-selectin glycoprotein ligand 1 (PSGL-1), scavenger receptor B2 (SCARB2), annexin II protein, sialylated glycan, and heparan sulfate.

    Synonyms

    P1D, Virion protein 1

  • Uniprot ID

    #BDI13007.1 (GeneBank ID)

    Sequence Note

    Gly1-Ser297

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  

  SDS-PAGE analysis of Enterovirus A71 (EV-A71) VP1 protein.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.