Leadgene Leadgene
Biotinylated Human IL-2, His-Avi Tag, HEK293
Catalog Number

LDG197PHM

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  • Specifications
    • Species of Origin

      Human

      Expression system

      HEK293

    • Affinity Tag

      His-Avi Tag (C-term)

      Conjugation

      Biontin

    • Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

      Purity

      >90% as determined by SDS-PAGE analysis.

    • Molecular weight

      The protein has a calculated MW of 18 kDa.
      The protein migrates as 12-15 kDa under reducing condition (SDS-PAGE analysis).

      Endotoxin level

      <0.1 EU per 1 μg of the protein by the LAL method.

    • Form

      Lyophilized

  • Background
    • Background

      Interleukin-2 (IL-2) is a key immunoregulatory cytokine primarily produced by activated T lymphocytes. IL-2 plays essential roles in T-cell proliferation, survival, differentiation, and immune tolerance through activation of the IL-2 receptor signaling pathway. It also promotes NK cell activation and regulates regulatory T-cell (Treg) homeostasis. IL-2 is widely used in immunology, cancer immunotherapy, cell expansion systems, and signal transduction studies due to its central role in adaptive immune responses and immune modulation.

      Synonyms

      Interleukin-2, IL2, T-cell growth factor, TCGF, Aldesleukin, Lymphocyte growth factor, T-cell stimulatory cytokine

    • Uniprot ID

      P60568

      Sequence Note

      Ala21-Thr153

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant Biotinylated Human IL-2.

    SDS-PAGE analysis of recombinant Biotinylated Human IL-2.

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  • Datasheet & Documents
    MSDS
    Manual
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