Biotinylated Human ASGPR1, His-Avi Tag, HEK293

Catalog Number

LDG195PHM

Datasheet

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• Specifications

  • Species of Origin

    Human

    Expression system

    HEK293

  • Affinity Tag

    His-Avi Tag (N-term)

    Conjugation

    Biotin

  • Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    Purity

    >95% as determined by SDS-PAGE analysis.

  • Molecular weight

    The protein has a calculated MW of 28.89 kDa.
    The protein migrates as 32-43 kDa under reducing condition (SDS-PAGE analysis).

    Endotoxin level

    <0.1 EU per 1 μg of the protein by the LAL method.

  • Form

    Lyophilized

• Background

  • Background

    Human Asialoglycoprotein Receptor 1 (ASGPR1), also known as hepatic lectin H1, is the major subunit of the asialoglycoprotein receptor complex predominantly expressed on hepatocytes. This C-type lectin maintains serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of desialylated glycoproteins. Additionally, ASGPR1 serves as a key receptor for Hepatitis B virus (HBV) entry and is widely used as a marker for liver-targeted drug delivery and hepatocyte biology research.

    Synonyms

    HL-1, Asialoglycoprotein receptor 1, Hepatic lectin 1, ASGR1, CLEC4H1, Galactose-specific receptor, Hepatocyte receptor

  • Uniprot ID

    P07306

    Sequence Note

    Gln62-Leu291

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration of 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  SDS-PAGE analysis of recombinant Biotinylated Human ASGPR1 Protein.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.