The immunoglobulin superfamily is a group of transmembrane proteins, contains a variable number of disulfide-stabilized motifs similar to immunoglobulins, associated with the adhesion, binding and recognition processes of cells. Receptor for advanced glycation endproducts (RAGE), a member of the immunoglobulin superfamily, not only binds to advanced glycation endproducts but also interacts with multiple ligands having common motifs. These interactions play important roles in various cellular processes, and associated with many human diseases.
Recommended dilution factor:
FACS: Assay dependent
Note: Working dilution for specific application should be determined by the investigator to obtain the best conditions.