Matrix metalloproteinases (MMPs) is a group of proteolytic enzymes that targets many extracellular proteins including other proteases, growth factors, cell surface receptors and adhesion molecules, plays an important role in many physiological and pathological processes. Matrix metalloproteinase-7 (MMP-7；matrilysin-1；PUMP-1), a member of the MMP family, can degrade a large series of proteins of the extracellular matrix and other substrates. MMP-7 is an important factor for normal tissue remodeling and wound healing and is associated with the occurrence and development of various tumors, thus may be a tumor biomarker and therapeutic target.
Recommended dilution factor:
FACS: Assay dependent
Note: Working dilution for specific application should be determined by the investigator to obtain the best conditions.