Interleukin-4 (IL-4) is a multifunctional anti-inflammatory cytokine produced by T helper 2 (TH2) cells, plays an important role in the allergic inflammation. This protein induces differentiation of naive helper T cells (TH0 cells) to TH2 cells, IgG class switch to IgE in B cells and alternative macrophage activation.
Recommended dilution factor:
FACS: Assay dependent
Note: Working dilution for specific application should be determined by the investigator to obtain the best conditions.