Interleukin-33 (IL-33), a member of the IL-1 family, is a nuclear alarmin cytokine expressed by various cell types. Unlike most other cytokines, IL-33 lacks a secretory signal peptide, and thus it is passively released during cell damage or tissue injury. IL-33 plays a crucial role in type-2 innate immunity through interaction with the ST2 receptor.
Recommended dilution factor:
FACS: Assay dependent
Note: Working dilution for specific application should be determined by the investigator to obtain the best conditions.