Hepatoma-derived growth factor (HDGF；also known as high mobility group protein 1-like 2, HMG-1L2) is a heparin-binding protein that is ubiquitously expressed in normal tissues and abnormally expressed in various malignancies. HDGF has various intracellular functions and localizes to the nucleus, and thus it is characterized as a mitogen for many cell types. As its promoting growth, suppressing differentiation and exhibiting angiogenic properties, HDGF plays a critical role in tumor progression.
Recommended dilution factor:
FACS: Assay dependent
Note: Working dilution for specific application should be determined by the investigator to obtain the best conditions.