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Leadgene Leadgene
Anti-GFAP Antibody [clone 10-2]
Catalog Number

LDG0236YA

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  • Overview

    Description

    Glial Fibrillary Acidic Protein (GFAP) is an intermediate filament protein predominantly expressed in astrocytes, a type of glial cell in the central nervous system. GFAP plays a crucial role in maintaining astrocyte structural integrity and supporting neuronal functions. Elevated GFAP levels are associated with neurodegenerative diseases, traumatic brain injuries, and gliomas, making it a key biomarker in neurological research and diagnostics. Anti-GFAP antibodies are widely used in immunohistochemistry, Western blot, and immunofluorescence to detect and study astrocyte activation, brain pathology, and glial cell function.

    Product Note

    Recommended dilution factor:
    ELISA: 1:5000-20000

    Note: Working dilution for specific application should be determined by the investigator to obtain the best conditions.

  • Specifications
    • Host

      Mouse

      Clonality

      Monoclonal

    • Isotype

      IgG2b

      Clone Name

      Clone 10-2

    • Immunogen

      Human GFAP Protein

      Reactivity

      Human

    • Application

      ELISA

      Conjugation

      Unconjugated

    • Concentration

      Lot dependent

      Buffer

      Phosphate Buffered Saline containing 0.03% Proclin300, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Form

      Liquid

  • Background
    • Synonyms

      GFAP, ALXDRD, glial fibrillary acidic protein

  • Instruction
    • Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

      Stability & Storage

      This product is stable after storage at:
      ● 2-8°C for 2 weeks under sterile conditions from date of receipt.
      ● -20°C or -80°C for 12 months under sterile conditions from date of receipt.
      Avoid repeated freeze/thaw cycles.
      Suggestion: Divide antibody into several vials. Keep only vials for usage at 2-8°C.

  • Image
    ELISA: Titration curve of anti-GFAP antibody in ELISA. Red: Human GFAP protein ; Black: BSA (negative control).

    ELISA: Titration curve of anti-GFAP antibody in ELISA. Red: Human GFAP protein ; Black: BSA (negative control).

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  • Datasheet & Documents
    MSDS
    Manual
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