Dengue virus belongs to the family Flaviviridae, genus Flavivirus and consists of four distinct serotypes (DENV1 to 4). Dengue virus is transmitted by mosquitos majorly of species Aedes aegypti and Aedes Albopictus that widespread around tropics and subtropics. During dengue virus maturation, host protease furin cleaves prM to M and pr. The peripheral pr peptide is retained on the virus particle at acidic pH. This virus-pr complex does not bind target membranes and thus to inhibit virus-membrane interaction and blocks virus fusion.
Recommended dilution factor:
FACS: Assay dependent
Note: Working dilution for specific application should be determined by the investigator to obtain the best conditions.