Dengue virus belongs to the family Flaviviridae, genus Flavivirus and consists of four distinct serotypes (DENV1 to 4). Dengue virus is transmitted by mosquitos majorly of species Aedes aegypti and Aedes Albopictus that widespread around tropics and subtropics. NS5 is the largest and the most conserved protein of Dengue virus, acting as both a RNA-dependent RNA polymerase and a RNA methyltransferase enzyme. The NS5 proteins are important for viral replication and can down-regulate the host immune interferon response.
Recommended dilution factor:
FACS: Assay dependent
Note: Working dilution for specific application should be determined by the investigator to obtain the best conditions.