LeadGMP® Human IL-6 Protein, His Tag, E. coli

カタログ番号

LDG006PHE-GMP

データシート

その他のドキュメント

パッケージと価格を読み込み中...

COA 検索

• 仕様

  • 由来種

    Human

    発現系

    Escherichia coli

  • アフィニティタグ

    His Tag (C-term)

    保存バッファー

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 8.0.

  • 純度

    >98% as determined by SDS-PAGE analysis.

    分子量

    The protein has a calculated MW of 21.8 kDa.
    The protein migrates as 22 kDa under reducing condition (SDS-PAGE analysis).

  • 活性

    Measure by its ability to induce proliferation in TF-1 cells The ED₅₀ for this effect is < 0.5 ng/mL. The specific activity of recombinant human IL-6 is approximately > 1 x 10⁸ IU/mg, which is calibrated against the human IL-6 WHO International Standard (NIBSC code: 89/548).

    エンドトキシン量

    <0.05 EU per 1 µg of the protein by the LAL method.

  • マイコプラズマ

    Not detected

    形状

    Lyophilized

• 背景

  • 背景

    Interleukin-6 (IL-6) is a pleiotropic, 22-28 kDa cytokine which plays fundamental role in the acute phase response, inflammation, bone metabolism, lymphocyte differentiation and cancer progression. Deregulation of IL-6 production was also found in several diseases, including rheumatoid arthritis, Alzheimer’s disease, autoimmune deficiency disease and different types of cancer.

    同義語

    Interleukin-6, B-cell stimulatory factor 2 , BSF-2, CTL differentiation factor , CDF, Hybridoma growth factor, Interferon beta-2 , IFN-beta-2

  • Uniprot ID

    P05231

    配列ノート

    Val30-Met212

• 使用説明

  • 溶解

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 0.5 mg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    配送

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • 安定性および保存

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

    製造仕様

    LeadGMP® recombinant proteins are manufactured in ISO 13485:2016 and GMP certified facility. The processes include:

    • Animal-free reagent and laboratory
    • Manufactured and tested under GMP guideline
    • Testing and traceability of raw material
    • Records of the maintenance and equipment calibration
    • Personnel training records
    • Batch-to-batch consistency
    • Documentation of QA control and process changes
    • Manufactured and tested under an ISO 13485:2016 certified quality management system
    • Stability monitor of product shelf-life

• 画像

  SDS-PAGE analysis of LeadGMP® IL-6, Human

  1

  /

  1

  合計   (1)

• レビュー

  

  この製品についてのご経験を共有してください。下のリンクから投稿いただけます。

  レビューを投稿

• 論文

  

  現在論文はありません。下のリンクからお知らせください。

  論文を投稿

• データシート & ドキュメント

  データシート

  MSDS

  マニュアル

  1

  /

  1

免責事項：For Research Use or Further Manufacturing Only.