LeadGMP® Human Activin A Protein, Tag Free, E. coli

カタログ番号

LDG026PHE-GMP

データシート

その他のドキュメント

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COA 検索

• 仕様

  • 由来種

    Human

    発現系

    Escherichia coli

  • アフィニティタグ

    Tag Free

    保存バッファー

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

  • 純度

    >97% as determined by SDS-PAGE analysis.

    分子量

    The protein has a calculated MW of 12.96 kDa.
    The protein migrates as 13-17 kDa under reducing condition (SDS-PAGE analysis).

  • 活性

    Measure by its ability to inhibit the proliferation of mouse MPC-11 cells. The ED₅₀ for this effect is <10 ng/mL. The specific activity of recombinant human Activin A is approximately >1.0 x 10³ IU/mg.

    エンドトキシン量

    <0.05 EU per 1 µg of the protein by the LAL method.

  • マイコプラズマ

    Negative

    形状

    Lyophilized

  • デフォルト

    Negative

• 背景

  • 背景

    Activin is the member of the TGF beta superfamily of cytokines. The current understanding of Activin A is classified as a hormone, a growth factor, and a cytokine. Depending on the different cell type, that overexpression of Activin A can either inhibit or promote cells division. There are important implications for tumor biology. Activin A also increase joint inflammation in rheumatoid arthritis (RA) and induces pathogenic mechanisms in the respiratory system.

    同義語

    Inhibin beta A chain, Activin beta-A chain, Erythroid differentiation protein , EDF

  • 配列ノート

    Gly311-Ser426

• 使用説明

  • 溶解

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 0.5 mg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    配送

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • 安定性および保存

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

    製造仕様

    LeadGMP® recombinant proteins are manufactured in ISO 13485:2016 and GMP certified facility. The processes include:

    • Animal-free reagent and laboratory
    • Manufactured and tested under GMP guideline
    • Testing and traceability of raw material
    • Records of the maintenance and equipment calibration
    • Personnel training records
    • Batch-to-batch consistency
    • Documentation of QA control and process changes
    • Manufactured and tested under an ISO 13485:2016 certified quality management system
    • Stability monitor of product shelf-life

• 画像

  SDS-PAGE analysis of LeadGMP® Activin A, Human

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  合計   (1)

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• 論文

  

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• データシート & ドキュメント

  データシート

  MSDS

  マニュアル

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免責事項：For Research Use or Further Manufacturing Only.