Anti-β-amyloid Antibody [Clone 85-1]

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• Übersicht

  Beschreibung

  Beta-amyloid (Aβ) is one of the intrinsically disordered proteins (IDPs) involved in Alzheimer's disease (AD) pathogenesis. This peptide derives from the sequential cleavage of a transmembrane glycoprotein, amyloid precursor protein (APP), by beta secretase and gamma secretase. The abnormal metabolism of APP result in excessive accumulation of Aβ, and triggers neurofibrillary tangles, oxidative stress, microglial activation, synaptic dysfunction, synaptic loss and the inflammatory response.

  Produktnotiz

  Recommended dilution factor:
  ELISA: 1:5000-20000
  WB:1: 1000-5000
  
  
  
  Note: Working dilution for specific application should be determined by the investigator to obtain the best conditions.

• Spezifikationen

  • Wirt

    Mouse

    Klonalität

    Monoclonal

  • Isotyp

    IgG2a

    Klonname

    clone 85-1

  • Immunogen

    Human beta-amyloid 1-42

    Reaktivität

    Human

  • Anwendung

    ELISA, WB

    Konjugation

    Unconjugated

  • Konzentration

    1 mg/mL

    Lagerpuffer

    Phosphate Buffered Saline containing 0.01% thimerosal, pH 7.4.

  • Spezifität

    Beta Amyloid (1-42)

    Form

    Liquid

• Anleitung

  • Versand

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    Stabilität & Lagerung

    This product is stable after storage at:

    • 2-8°C for 2 weeks under sterile conditions from date of receipt.
    • -20°C or -80°C for 12 months under sterile conditions from date of receipt.

    Avoid repeated freeze/thaw cycles.
    Suggestion: Divide antibody into several vials. Keep only vials for usage at 2-8°C.

• Bild

  ELISA titration of Anti-β-amyloid (1-42) Antibody [clone 85-1]

  Dot blot analysis of Anti-β-amyloid (1-42) Antibody [clone 85-1].

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• Datenblatt & Dokumente

  Datenblatt

  MSDS

  Handbuch

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Haftungsausschluss：For Research Use or Further Manufacturing Only.